Title

Quantitation of complement proteins in rheumatic disease

Document Type

Article

Publication Date

4-1-1983

Abstract

Complement proteins serve a critical function in the non-antigen-specific elimination of foreign substances and organisms and of immune complexes. Studies of genetic and acquired alterations of complement proteins have provided insights into the pathophysiology of a number of rheumatic diseases, especially those in which immune complexes are believed to have a role in pathogenesis. Complement levels may be helpful in the management of some patients with SLE or vasculitis, and in evaluation of synovial, pleural and pericardial fluids.

Publication Title

Clinics in rheumatic diseases

First Page

177

Last Page

198

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