Quantitation of complement proteins in rheumatic disease
Complement proteins serve a critical function in the non-antigen-specific elimination of foreign substances and organisms and of immune complexes. Studies of genetic and acquired alterations of complement proteins have provided insights into the pathophysiology of a number of rheumatic diseases, especially those in which immune complexes are believed to have a role in pathogenesis. Complement levels may be helpful in the management of some patients with SLE or vasculitis, and in evaluation of synovial, pleural and pericardial fluids.
Clinics in rheumatic diseases
George, D. L., & Glass, D. (1983). Quantitation of complement proteins in rheumatic disease. Clinics in rheumatic diseases, 9 (1), 177-198. Retrieved from https://scholarcommons.towerhealth.org/gme_int_med_resident_program_read/418