Strongyloides Stercoralis in Immunocompromised Patients: A Case Series

Authors

Fizza Hirani, Department of Medicine, Reading Hospital - Tower Health, West Reading, PAFollow
Olubunmi Oladunjoye, Department of Medicine, Reading Hospital-Tower Health, West Reading, PAFollow
Adeolu Oladunjoye, Division of Medical Critical Care, Boston Children's Hospital, Boston, MA
Nitin Patel, Department of Infectious Disease, Reading Hospital - Tower Health, West Reading, PA.Follow

Document Type

Article

Publication Date

9-2020

Abstract

Strongyloides hyperinfection diagnosis has been associated with high mortality. We present a case series of 3 immunocompromised patients who had severe infection of Strongyloides including 1 fatal case. The first patient was on chronic steroids and cyclophosphamide for acquired hemophilia. She was admitted for sepsis with bacteremia and multifocal pneumonia, acute respiratory distress syndrome, and sputum positive for Strongyloides. The second patient was on chronic steroids and infliximab and developed septic shock secondary to multifocal pneumonia, enterococcal bacteremia, and disseminated strongyloidiasis with hyperinfection. The third patient on chronic steroids and immunosuppressive therapy presented with worsening dyspnea and cough and was found to have strongyloidiasis in bronchoalveolar lavage fluid. Early identification and treatment of at-risk population particularly the immunocompromised could potentially reduce the risk of mortality.

Publication Title

Infectious Diseases in Clinical Practice

Volume

28

Issue

5

First Page

291

Last Page

294

Recommended Citation

Hirani, F., Oladunjoye, O., Oladunjoye, A., & Patel, N. (2020). Strongyloides Stercoralis in Immunocompromised Patients: A Case Series. Infectious Diseases in Clinical Practice, 28 (5), 291-294. https://doi.org/doi: 10.1097/IPC.0000000000000871