Non-Hodgkin's lymphoma masquerading as splenic abscess: A case report.

Document Type

Article

Publication Date

9-1-2022

Abstract

Background: Non-Hodgkin's lymphoma (NHL) is a monoclonal proliferation of lymphoid cells from B lineage. Although NHLs are primarily hematological tumors of lymph nodes but rarely can involve extranodal sites such as the spleen.

Case report: A 29-year-old female patient presented with low-grade fever, cough, anemia, weight loss, tender left hypochondrium, and splenomegaly. A hypodense lesion in the spleen with central necrosis, having strong positivity for common leukocyte antigen (LCA), CD 20, and CD 10, led to a diffuse large B cell lymphoma diagnosis. The patient had an excellent clinical post-splenectomy response to combination chemotherapy and immunotherapy.

Conclusion: NHL can present with symptomatic extra-nodal involvement without enlarged lymph nodes.

Publication Title

Ann Med Surg (Lond)

Volume

81

First Page

104449

Last Page

104449

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