Non-Hodgkin's lymphoma masquerading as splenic abscess: A case report.
Background: Non-Hodgkin's lymphoma (NHL) is a monoclonal proliferation of lymphoid cells from B lineage. Although NHLs are primarily hematological tumors of lymph nodes but rarely can involve extranodal sites such as the spleen.
Case report: A 29-year-old female patient presented with low-grade fever, cough, anemia, weight loss, tender left hypochondrium, and splenomegaly. A hypodense lesion in the spleen with central necrosis, having strong positivity for common leukocyte antigen (LCA), CD 20, and CD 10, led to a diffuse large B cell lymphoma diagnosis. The patient had an excellent clinical post-splenectomy response to combination chemotherapy and immunotherapy.
Conclusion: NHL can present with symptomatic extra-nodal involvement without enlarged lymph nodes.
Ann Med Surg (Lond)
Khan, Q., Mumtaz, A., Baqi, A., Ain, H., Mahfooz, R., Asim, N., Iram, S., Hussien Mohamed Ahmed, K., Tahir, M., & yousaf, z. (2022). Non-Hodgkin's lymphoma masquerading as splenic abscess: A case report.. Ann Med Surg (Lond), 81, 104449-104449. https://doi.org/https://doi.org/10.1016%2Fj.amsu.2022.104449