Postoperative Mortality Following Metabolic and Bariatric Surgery for Obesity in Individuals with Prader-Willi Syndrome

Authors

Stephan R. Myers, Division of Bariatric Surgery, St. Christopher's Hospital for Children - Tower Health, Philadelphia, PAFollow
Gunnar Wolfe
Aaron Hechtman DO, Reading Hospital -Tower Health Weight Loss Surgery and Wellness Center, Wyomissing, PAFollow
Robert Dillard, Reading Hospital -Tower Health Weight Loss Surgery and Wellness Center, Wyomissing, PA
Renee Riddle, Reading Hospital -Tower Health Weight Loss Surgery and Wellness Center, Wyomissing, PAFollow
Vesta Salehi MD, Division of Bariatric Surgery, St. Christopher's Hospital for Children - Tower Health, Philadelphia, PAFollow
John Fam, Reading Hospital -Tower Health Weight Loss Surgery and Wellness Center, Wyomissing, PAFollow

Document Type

Abstract

Publication Date

6-1-2024

Abstract

Stephan Myers Sinking Spring PA¹, Gunnar Wolfe Corona CA², Aaron Hechtman Wyomissing PA³, Robert Dillard³, Renee Riddle Wyomissing PA³, Vesta Salehi philadelphia PA⁴, John Fam Wyomissing PA³ St. Chrristopher's Hospital for Children¹ University of California, Riverside²Tower Health³ St. Christopher's Hospital for Children⁴ Background: The risk of postoperative mortality after metabolic and bariatric surgery (MBS) is often considered to be too high for individuals with Prader-Willi Syndrome (PWS) Objectives: Determine the rate of postoperative mortality following initial MBS for the treatment of obesity in PWS. Methods: A systematic review of articles in the English language of MBS in PWS was performed using PubMed, Embase and Cochrane Central identifying 254 citations extending from 1974 to July 2022. Twenty-eight articles in the English language were identified that reported on a total of 103 patients having a primary MBS operation. Results: There were 3 deaths reported within 12 months following 103 MBS operations performed for obesity on PWS individuals for a postoperative mortality rate of 2.9%. Two reported in 1985 following a jejunoileal bypass which is no longer performed, and one reported in 1996 following a gastric band placement. There has been no postoperative mortality recorded in the 71 individuals with PWS that had MBS since 1996. No postoperative mortality was reported any of the individuals with PWS (87) that had a primary laparoscopic gastric sleeve (n=34), gastric bypass (n=23) or biliopancreatic diversion with or without duodenal switch (n=30). Conclusion: There has been no postoperative mortality reported in a primary laparoscopic gastric sleeve, gastric bypass or biliopancreatic bypass with or without a duodenal switch. Therefore, individuals with PWS who suffer from severe obesity should not be excluded from being evaluated for MBS.

Publication Title

Surgery for Obesity and Related Diseases

Volume

20

Issue

6 Supplement

First Page

S13

Last Page

S13

Comments

40TH ANNUAL MEETING OF THE AMERICAN SOCIETY FOR METABOLIC AND BARIATRIC SURGERY held 2024-06-09 to 2024-06-13 in San Diego, CA, USA.

Recommended Citation

Myers, S. R., Wolfe, G., Hechtman, A., Dillard, R., Riddle, R., Salehi, V., & Fam, J. (2024). Postoperative Mortality Following Metabolic and Bariatric Surgery for Obesity in Individuals with Prader-Willi Syndrome. Surgery for Obesity and Related Diseases, 20 (6 Supplement), S13-S13. https://doi.org/https://doi.org/10.1016/j.soard.2024.04.057