Document Type
Article
Publication Date
11-2017
Abstract
We present a case of a 79-year-old male who presented with retroperitoneal hematoma a week after motor vehicle accident. Prior history and family history of bleeding were nonsignificant. His activated partial thromboplastin time was found to be prolonged in the emergency department. Further workup with coagulation studies showed decreased factor VIII, vWF antigen, and vWF:ristocetin cofactor assay, and negative Bethesda assay, indicating acquired von Willebrand disease. Immunofluorescence to find an underlying etiology was suggestive of MGUS. Management of AvWD depends on controlling active bleeding and treating the underlying cause. He was treated with factor VIII, haemate-p, rituximab, two cycles of IVIg, and three weeks of oral steroids.
Publication Title
Case Reports in Oncological Medicine
Recommended Citation
Basnet, S., Lin, C., Dhital, R., Mir, I., Mohanty, E., Tharu, B., Ghimire, S., & Poudel, D. (2017). Acquired von Willebrand disease associated with monoclonal gammopathy of unknown significance. Case Reports in Oncological Medicine https://doi.org/10.1155/2017/9295780
Comments
This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.