Rapidly Progressive Granulomatous Amoebic Encephalitis in a Diabetic Individual

Authors

Anish C. Paudel, Internal Medicine, The Reading Hospital, West Reading, USA.Follow
Nitin Patel, Infectious Disease, The Reading Hospital, West Reading, USA.
Jonathan Quang, Emergency Medicine, University of California Irvine Medical Center, Irvine, USA.
Courtney Casella, Emergency Medicine, The Reading Hospital, West Reading, USA.
Adam Sigal, Emergency Medicine, The Reading Hospital, West Reading, USA.
Prem Parajuli, Internal Medicine, The Reading Hospital, West Reading, USA.
Olubunmi Oladunjoye, Internal medicine, The Reading Hospital, West Reading, USA.
Ibiyemi O. Oke, Internal Medicine, The Reading Hospital, West Reading, USA.
Suravi Khanal, Internal Medicine, Manipal College of Medical Sciences, Pokhara, NPL.
Kristina Bhattarai, Internal Medicine, Nepal Medical College, Kathmandu, NPL.

Document Type

Article

Publication Date

11-1-2021

Abstract

We present a case of rapidly progressive granulomatous amoebic encephalitis caused by in an individual with diabetes mellitus. Our patient presented with occipital headache, blurry vision, confusion, and gait imbalance of one week's duration. Brain imaging revealed numerous peripheral ring-enhancing lesions concerning malignancy. Brain biopsy was consistent with infection. He passed away 45 days after presentation despite being treated with a five-drug regimen. This case highlights the importance of considering amoebic brain infections, especially with ring-enhancing lesions on imaging. There are opportunities to design modalities for rapid diagnosis and better treatment.

Publication Title

Cureus

Volume

13

Issue

11

First Page

e19336

Recommended Citation

Paudel, A. C., Patel, N., Quang, J., Casella, C., Sigal, A., Parajuli, P., Oladunjoye, O., Oke, I. O., Khanal, S., & Bhattarai, K. (2021). Rapidly Progressive Granulomatous Amoebic Encephalitis in a Diabetic Individual. Cureus, 13 (11), e19336. https://doi.org/10.7759/cureus.19336