A Case of Macrophage Activation Syndrome Manifesting as the Initial Presentation of Systemic Lupus Erythematosus.

Authors

Amar Suwal, Dept of Internal Medicine, Reading Hospital-Tower Health, West Reading, PAFollow
Biraj Shrestha, Dept of Internal Medicine, Reading Hospital-Tower Health, West Reading, PAFollow
Anish Paudel, Dept of Internal Medicine, Reading Hospital-Tower Health, West Reading, PAFollow
Rubina Paudel, Dept of Internal Medicine, Reading Hospital-Tower Health, West Reading, PAFollow
Sijan Basnet, Dept of Internal Medicine, Reading Hospital-Tower Health, West Reading, PAFollow

Document Type

Article

Publication Date

6-1-2022

Abstract

Macrophage activation syndrome (MAS) is a potentially fatal complication of an autoimmune rheumatologic disease characterized by overwhelming inflammation, multiorgan failure, and high mortality if untreated. We report a rare case of a 56-year-old man who presented with fever for three weeks and had a constellation of clinical features and laboratory findings, meeting the diagnostic criteria for systemic lupus erythematosus (SLE) and SLE-associated MAS. He was treated with high dose intravenous corticosteroid and hydroxychloroquine, resulting in resolution of fever and dramatic clinical improvement.

Publication Title

Cureus

Volume

14

Issue

6

First Page

26375

Last Page

26375

Recommended Citation

Suwal, A., Shrestha, B., Paudel, A., Paudel, R., & Basnet, S. (2022). A Case of Macrophage Activation Syndrome Manifesting as the Initial Presentation of Systemic Lupus Erythematosus.. Cureus, 14 (6), 26375-26375. https://doi.org/https://doi.org/10.7759%2Fcureus.26375