Imaging, Histopathologic, and Treatment Nuances of Pulmonary Carcinosarcoma.
Document Type
Article
Publication Date
9-17-2017
Abstract
A 76-year-old female with coronary artery disease, chronic obstructive pulmonary disease, diabetes mellitus type II, and 40 pack-year smoking history presented with a four-day history of cough, productive of green-yellow sputum. Chest X-ray revealed opacification of the left upper lung field, and computed tomography (CT) of the chest showed a large cavitary lesion invading the T2-T3 vertebral bodies, extending into the epidural space, giving rise to mild cord compression. Biopsy of the lesion revealed a poorly differentiated neoplasm composed of distinct epithelial and mesenchymal components, consistent with carcinosarcoma. A metastatic workup was negative. Primary lung carcinosarcoma is a rare tumour that can demonstrate an especially aggressive clinical course; diagnosis is often nuanced by limited sampling at initial presentation, especially in a setting of advanced disease and debility that precludes consideration for upfront resection or more extensive, invasive sampling.
Publication Title
Case Rep Radiol
Volume
2017
First Page
8135957
Last Page
8135957
Recommended Citation
Gleason, T., Haas, M., & Le, B. (2017). Imaging, Histopathologic, and Treatment Nuances of Pulmonary Carcinosarcoma.. Case Rep Radiol, 2017, 8135957-8135957. https://doi.org/https://doi.org/10.1155%2F2017%2F8135957