Decadal Analysis of Acute Myocardial Infarction Mortality Trends in the African American Population in the United States (1999-2020)

Document Type

Abstract

Publication Date

8-1-2024

Abstract

Background Myocardial infarction remains a leading cause of mortality in the African American population, warranting an examination of regional and demographic trends to inform targeted health policies. Methods We used the Centers for Disease Control and Prevention’s WONDER (Wide‐Ranging Online Data for Epidemiologic Research) death certificate database to analyze acute myocardial infarction (AMI) mortality from 1999 to 2020 in African Americans and overall adults aged 25 and older, utilizing ICD-10 codes for AMI. Age-adjusted mortality rates (AAMRs) per 100,000 persons were calculated and stratified by year, sex, race, and geographic region. Joinpoint regression was used to assess mortality trends and average annual percentage changes with 95% confidence intervals (CIs). Results From 1999-2020, there were 3,015,339 total deaths due to AMI in adults aged 25 and older, with 317,504 occurring among African Americans. African Americans had the highest AAMR, 71.5, followed by Whites, 63.5, and lowest in Asians, 32.6. Overall, AAMR decreased in the African American population from 128.5 in 1999 to 48.5 in 2020, with an average annual percentage change (AAPC) of -5.29 (95 % CI -5.69 to -4.9). In African American females, AAMR decreased from 109 to 37.6, with an AAPC of -5.85 (95 % CI -6.23 to -5.83). AAMR in African American males declined from 157.8 to 63.4, with an AAPC of -4.95 (95% CI -5.37 to -4.51). African American males had a higher AAMR (88.6) than females (59.3). Regionally, AAMR was highest in the South (77.6) and lowest in the Northeast (57.6) in African Americans. Conclusion Persistent disparities persist in African Americans despite declining mortality. Regional variations, notably a higher AAMR in the South, emphasize the need for targeted policies addressing social determinants of health to mitigate disparities and enhance healthcare access. [Formula presented]

Publication Title

Cardiovascular Revascularization Medicine

Volume

65 Supplement

First Page

18

Last Page

19

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