Incidence and Predictors of Growth Modulation and Overcorrection after Anterior Vertebral Body Tethering.

Document Type

Article

Publication Date

2-19-2025

Abstract

STUDY DESIGN: Retrospective review of a prospectively collected single-center adolescent idiopathic scoliosis (AIS) database.

OBJECTIVE: To evaluate the incidence and predictors of growth modulation and overcorrection after vertebral body tethering (VBT) in AIS.

BACKGROUND: Little data exists regarding which AIS patients will exhibit growth modulation and/or overcorrection after VBT compared to those whose curve correction will remain unchanged (no modulation).

MATERIALS AND METHODS: A total of 279 patients with AIS with a minimum 2-year follow-up (range 2-10 years) were included. There were 262 thoracic and 65 thoracolumbar VBT surgeries performed. Univariate and multivariate regression analyses were performed to identify the potential clinical/radiographic predictive factors for growth modulation and overcorrection.

RESULTS: Patients with growth modulation and those with no modulation after thoracic VBT were significantly more immature (younger, premenarchal, lower Sanders score/Risser grade, open triradiate cartilage [TRC]) and physically smaller (lower height, weight, and body mass index [BMI]; P

CONCLUSION: AIS patients with open-TRC and lower BMI had a statistically higher rate of thoracic growth modulation and overcorrection after VBT in multivariate analysis. Preoperative and first-erect curve magnitudes did not affect the incidence of growth modulation.

Publication Title

Spine (Phila Pa 1976)

Comments

online ahead of print

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