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Abstract

Direct oral anticoagulants (DOACs) are a novel class of anticoagulants. They include rivaroxaban, apixaban, edoxaban, and dabigatran. Benefits of DOACs over many older anticoagulants include oral administration, quicker onset of action, less monitoring requirements, and fewer drug interactions. Since the DOACs were first introduced, their use has increased tremendously. This article aims to help providers become more familiar with DOACs and the specific factors that may impact prescribing practices. Several drugs used for the reversal of DOACs will also be discussed. Lastly, the article will describe certain situations in which warfarin is preferred over DOACs.

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