Hemithioindigo-Based Visible Light-Activated Molecular Machines Kill Bacteria by Oxidative Damage.

Authors

Ana L Santos
Alexis van Venrooy
Anna K Reed
Aaron M Wyderka
Víctor García-López
Lawrence B Alemany
Antonio Oliver
George P Tegos, Office of Research, Reading Hospital, Tower Health, 420 S. Fifth Avenue, West Reading, PA, 19611, USA.Follow
James M Tour

Document Type

Article

Publication Date

10-2022

Abstract

Antibiotic resistance is a growing health threat. There is an urgent and critical need to develop new antimicrobial modalities and therapies. Here, a set of hemithioindigo (HTI)-based molecular machines capable of specifically killing Gram-positive bacteria within minutes of activation with visible light (455 nm at 65 mW cm

Publication Title

Adv Sci (Weinh)

Volume

9

Issue

30

First Page

2203242

Last Page

2203242

Recommended Citation

Santos, A., van Venrooy, A., Reed, A., Wyderka, A., García-López, V., Alemany, L., Oliver, A., Tegos, G., & Tour, J. (2022). Hemithioindigo-Based Visible Light-Activated Molecular Machines Kill Bacteria by Oxidative Damage.. Adv Sci (Weinh), 9 (30), 2203242-2203242. https://doi.org/https://doi.org/10.1002%2Fadvs.202203242